Interactions between Cryptosporidium, Enterocytozoon, Giardia and Intestinal Microbiota in Bactrian Camels on Qinghai-Tibet Plateau, China

Cryptosporidium spp., Enterocytozoon bieneusi, and Giardia duodenalis are zoonotic pathogens commonly found in the intestinal tract of mammalian hosts including livestock humans. The prevalence these eukaryote microorganisms domestic animals their interaction with microbiota not yet fully recognized. We analyzed composition metagenomics functional characterization Cluster Orthologous (COG) Bactrian camels, which were raised on Qinghai-Tibet Plateau, Northwest China. Thus, fecal samples collected from to determine parasite infection profile microbiota. Analysis at genus level revealed important features between parasites bacterial community. Coprococcus Prevotella more abundant while Akkermansia had lower relative abundance E. bieneusi infection. Bacteria Akkermansia, Lactococcus, Oxalobacter, Sphaerochaeta, Paludibacter, Fibrobacter, Anaerovibrio, Pseudomonas, Mogibacterium, Pseudoramibacter_Eubacterium, YRC22, Flexispira, SMB53, AF12, Roseburia genera under-presented Oscillospira over-presented when G. was present. Meanwhile, spp. co-infected showed Allobaculum, Rikenella, Shuttleworthia, Epulopiscium, Bilophila, Dorea, TG5. Results demonstrate microbiota, provide informative link for understanding co-evolution bacteria animals.